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Chicken and Shrimp Alfredo

"How to Make the Best Chicken and Shrimp Alfredo at Home (Step-by-Step Guide)"

A creamy and flavorful Chicken and Shrimp Alfredo, made with tender chicken, succulent shrimp, and a rich Parmesan sauce, served over fettuccine pasta. Perfect for a quick and indulgent dinner that everyone will love!
Prep Time 10 minutes
Cook Time 20 minutes
Total Time 30 minutes
Course Main Course
Cuisine American, Cajun, Italian
Servings 4
Calories 1013 kcal

Ingredients
  

For the Chicken & Shrimp:

  • 2 chicken breasts cut into 1-inch pieces
  • 12 oz shrimp peeled and deveined
  • 2 tablespoons butter
  • 1 tablespoon olive oil
  • 1 teaspoon salt
  • ½ teaspoon black pepper
  • ½ teaspoon garlic powder

For the Alfredo Sauce:

  • 3 tablespoons butter
  • 1 cup heavy cream
  • 4 oz cream cheese
  • 1 cup grated Parmesan cheese
  • 2 teaspoons minced garlic
  • ¼ cup reserved pasta water optional
  • 1 teaspoon Cajun seasoning optional for a flavor boost

For the Pasta:

  • 12 oz fettuccine or other pasta of choice

Instructions
 

  • Prep the ingredients:
  • Cut the chicken into 1-inch pieces and season with salt, pepper, and garlic powder.
  • Thaw shrimp if frozen, pat them dry, and season them with salt and pepper.
  • Cook the chicken:
  • In a large skillet, heat olive oil and 1 tablespoon butter over medium-high heat.
  • Add the chicken pieces and cook until golden brown, about 5-7 minutes.
  • Remove the chicken from the skillet and set aside.
  • Cook the shrimp:
  • In the same skillet, add another tablespoon of butter and sauté the shrimp until they turn pink and opaque, about 2-3 minutes.
  • Remove shrimp from the skillet and set aside.
  • Make the Alfredo sauce:
  • In the same skillet, melt 3 tablespoons of butter over medium heat.
  • Add minced garlic and sauté for 30 seconds until fragrant.
  • Stir in heavy cream and cream cheese until smooth.
  • Gradually add the grated Parmesan cheese, whisking continuously to avoid clumps.
  • Add Cajun seasoning for a flavor boost if desired.
  • If the sauce is too thick, add a splash of pasta water until the desired consistency is reached.
  • Combine:
  • Return the cooked chicken and shrimp to the skillet.
  • Stir everything together to coat the proteins in the creamy Alfredo sauce.
  • Prepare the pasta:
  • Meanwhile, cook the pasta according to package instructions, drain, and set aside.
  • Serve:
  • Plate the fettuccine, top with the chicken and shrimp Alfredo mixture, and garnish with freshly grated Parmesan and parsley.

Notes

  • For a lighter version, substitute part of the heavy cream with milk or broth.
  • Fresh herbs like parsley or basil add a burst of color and freshness when sprinkled on top before serving.
  • Fettuccine is a classic choice for this dish, but you can use other types of pasta like linguine or tagliatelle.
  • To add extra flavor, consider sprinkling a pinch of smoked paprika or a squeeze of lemon juice before serving.
Keyword Alfredo Sauce, Cajun Alfredo, Chicken Alfredo, Chicken and Shrimp Alfredo, Creamy Alfredo, Fettuccine Alfredo, Homemade Alfredo, Pasta Dish, Quick Pasta Dinner, Shrimp Alfredo